Jacek Hawiger Selected Research

Triglycerides (Triacylglycerol)

1/2021	Hyperlipidemic hypersensitivity to lethal microbial inflammation and its reversal by selective targeting of nuclear transport shuttles.
9/2013	Targeting nuclear import shuttles, importins/karyopherins alpha by a peptide mimicking the NFκB1/p50 nuclear localization sequence.
4/2013	Nuclear transport modulation reduces hypercholesterolemia, atherosclerosis, and fatty liver.

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Jacek Hawiger Research Topics

Disease

13	Inflammation (Inflammations) 01/2023 - 04/2004
5	Sepsis (Septicemia) 01/2023 - 05/2016
3	Pneumonia (Pneumonitis) 01/2018 - 05/2009
2	Fibrosis (Cirrhosis) 03/2024 - 01/2020
2	Sarcoma (Soft Tissue Sarcoma) 03/2024 - 01/2020
2	Fatty Liver 01/2021 - 04/2013
2	Necrosis 01/2019 - 08/2005
2	Autoimmune Diseases (Autoimmune Disease) 10/2016 - 10/2010
2	Atherosclerosis 09/2013 - 04/2013
2	Vascular System Injuries 01/2012 - 05/2009
1	Non-alcoholic Fatty Liver Disease 03/2024
1	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 03/2024
1	Hypersensitivity (Allergy) 01/2021
1	Septic Shock (Toxic Shock Syndrome) 01/2019
1	Hearing Loss (Hearing Impairment) 01/2018
1	Purpura Fulminans 01/2018
1	Multiple Organ Failure (MODS) 01/2017
1	Thrombocytopenia (Thrombopenia) 01/2017
1	Nervous System Diseases (Neurological Disorders) 10/2016
1	Neoplasms (Cancer) 10/2016
1	Multiple Sclerosis 10/2016
1	Neonatal Sepsis 05/2016
1	Endotoxemia 05/2016
1	Shock 01/2014
1	Acute Lung Injury 01/2014
1	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 09/2013
1	Hypercholesterolemia 04/2013
1	Body Weight (Weight, Body) 04/2013
1	Hyperlipidemias (Hyperlipidemia) 04/2013
1	Laminopathies 01/2013
1	Infections 01/2012
1	Hemorrhage 01/2012
1	Anthrax 01/2012
1	Hypoxia (Hypoxemia) 01/2012
1	Blindness (Hysterical Blindness) 10/2010
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 10/2010
1	Acute Kidney Injury (Acute Renal Failure) 07/2008
1	Hemolytic-Uremic Syndrome 07/2008

Drug/Important Bio-Agent (IBA)

7	Transcription Factors (Transcription Factor)IBA 01/2021 - 05/2009
7	CytokinesIBA 10/2016 - 08/2005
5	Virulence Factors (Pathogenicity Factors)IBA 01/2019 - 07/2008
4	Cell-Penetrating PeptidesIBA 03/2024 - 05/2009
4	Proteins (Proteins, Gene)FDA Link 08/2014 - 08/2005
3	Karyopherins (Importin)IBA 01/2021 - 01/2014
3	Triglycerides (Triacylglycerol)IBA 01/2021 - 04/2013
3	NF-kappa B (NF-kB)IBA 01/2017 - 05/2009
3	ChemokinesIBA 01/2014 - 10/2010
3	cSN50.1 peptideIBA 01/2014 - 04/2013
3	staphylococcal enterotoxin BIBA 05/2009 - 04/2004
2	CollagenIBA 03/2024 - 01/2020
2	CholesterolIBA 01/2021 - 09/2013
2	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 09/2013
2	Peptides (Polypeptides)IBA 01/2019 - 05/2009
2	alpha KaryopherinsIBA 01/2019 - 01/2017
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2018 - 01/2012
2	InterleukinsIBA 05/2016 - 01/2012
2	LipopolysaccharidesIBA 01/2014 - 08/2005
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 03/2024
1	DNA (Deoxyribonucleic Acid)IBA 03/2024
1	RNA-Binding Protein FUSIBA 03/2024
1	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2020
1	IntegrinsIBA 01/2020
1	ErbB Receptors (EGF Receptor)IBA 01/2020
1	Nuclear Proteins (Protein, Nuclear)IBA 01/2020
1	RNA (Ribonucleic Acid)IBA 01/2020
1	LipidsIBA 01/2019
1	Sterol Regulatory Element Binding ProteinsIBA 01/2019
1	GalactosamineIBA 01/2019
1	VaccinesIBA 01/2018
1	E-SelectinIBA 01/2017
1	Inosine Monophosphate (IMP)IBA 01/2017
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 01/2017
1	P-SelectinIBA 01/2017
1	L-SelectinIBA 01/2017
1	beta Karyopherins (Importin-beta)IBA 01/2017
1	STAT1 Transcription FactorIBA 01/2017
1	Interleukin-2 (IL2)IBA 10/2016
1	Interleukin-18 (Interleukin 18)IBA 05/2016
1	Interleukin-17 (Interleukin 17)IBA 05/2016
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2014
1	EndotoxinsIBA 01/2014
1	Interleukin-10 (Interleukin 10)IBA 01/2014
1	Blood Glucose (Blood Sugar)IBA 04/2013
1	LDL Receptors (LDL Receptor)IBA 04/2013
1	LaminsIBA 01/2013
1	Ciprofloxacin (Cipro)FDA LinkGeneric 01/2012
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2012
1	Biomarkers (Surrogate Marker)IBA 01/2012
1	ExotoxinsIBA 01/2012
1	Erythropoietin FDA Link 01/2012
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2012
1	Capsules (Microcapsules)IBA 01/2012
1	Insulin (Novolin)FDA Link 10/2010
1	SuperantigensIBA 05/2009
1	Immunotoxins (Immunotoxin)IBA 05/2009
1	Shiga Toxins (Vero Toxin)IBA 07/2008
1	Concanavalin AIBA 08/2005

Therapy/Procedure

6	Therapeutics 01/2023 - 08/2005
2	Immunotherapy 10/2016 - 10/2010
1	Surgical Amputation (Amputations) 01/2018